JWH-018

$350.00$3,000.00

Full Chemical Name:  JWH-018
Systematic IUPAC Name Naphthalen-1-yl-(1-pentylindol-3-yl)methanone
CAS Number 209414-07-3
ChemSpider Number 8558143
Molecular Formula C24H23NO
Molecular Mass 341.45 g/mol

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Description

Naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH018) is a mildly selective agonist of the peripheral cannabinoid (CB2) receptor, derived from the aminoalkylindole WIN 55,212-2. The Ki values for binding central cannabinoid (CB1) and CB2 receptors are 9.0 and 2.94 nM, respectively, for a CB1:CB2 ratio of 3.06.1 Its effects on suppression of spontaneous activity, maximum possible antinociceptive effect in the tail-flick assay, and rectal temperature are comparable to those of WIN 55,212-2 when tested in rats.

It is a research chemical that belongs to the naphthoylindole family. JWH-081 as all the other research chemicals in the JWH group is a synthetic cannabinoid with analgesic effects. Its full chemical name is 4-methoxynaphthalen- 1-yl- (1-pentylindol- 3-yl)methanone with chemical formula as C25H25NO2 and molecular mass 371.47 g/mol.

Naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH018) is an aminoalkylindole used as an active ingredient of products sold as cannabis substitutes. When smoked, JWH-018 produces cannabimimetic effects in doses lower than the doses of Δ9-tetrahydrocannabinol (THC) needed to produce effects of similar strength (higher potency).

JWH 018 is an analytical reference material categorized as a synthetic cannabinoid.1 It has been found in Spice/K2-type herbal blends and may have neurotoxic properties. JWH 018 is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.

Synonyms
Synonyms
  • AM678
Technical Information
Formal Name…………………….1-naphthalenyl(1-pentyl-1H-indol-3-yl)-methanone
CAS Number……………………..209414-07-3
Molecular Formula……………..C24H23NO
Formula Weight…………………341.5
Purity……………………………….≥98%
Formulation………………………A neat solid
SMILES……………....………….CCCCCn1cc(C(=O)c2cccc3ccccc23)c2ccccc12
InChi Code………………………InChI=1S/C24H23NO/c1-2-3-8-16-25-17-22(20-13-6-7-15-23(20)25)24(26)21-14-9-11-18-10-4-5-12-19(18)21/h4-7,9-15,17H,2-3,8,16H2,1H3
InChi Key………………………JDNLPKCAXICMBW-UHFFFAOYSA-N
DEA Schedule………………..I
Shipping & Storage Information
Storage……………-20°C
Shipping…………..Room Temperature in continental US; may vary elsewhere
Stability………….... ≥ 73 months

Additional information

Quantity

25g, 50g, 100g, 500g